Seyboth Wild made his ATP main draw debut at the 2018 Brasil Open after receiving a wildcard into the singles main draw. He won his first Challenger title at Guayaquil defeating Bolivian Hugo Dellien on November 3, 2019.

He reached his first third round at a Grand Slam tournament at the US Open 2017 where he was defeated by fellow italian Paolo Lorenzi. Since then he reached the second round or better at each of the Grand Slams. Updated through the 2021 US Open.